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RDH12 / LCA3

retinol dehydrogenase 12 (all-trans/9-cis/11-cis)

Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments.

Gene Name: retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Synonyms: RDH12, LCA13, LCA3, Retinol dehydrogenase 12, SDR7C2
Target Sequences: Q96NR8 Q96NR8

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
RDH12 / LCA3 (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
His-SUMO (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
RDH12 / LCA3 Protein
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E. coli
His-SUMO
51.04 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RDH12 / LCA3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RDH12 / LCA3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.9 kDa
20 µg/$150
RDH12 / LCA3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34.9 kDa
100 µg/$494
RDH12 / LCA3 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
RDH12 / LCA3 Protein - 12.5% SDS-PAGE of human RDH12 stained with Coomassie Blue
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Wheat Germ Extract
GST
61.5 kDa
2 µg/$439
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).