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RCBTB1 is a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.
Gene Name: | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
Synonyms: | RCBTB1, CLLD7, GLP, E4.5, RP11-185C18.1, CLLL7 |
Target Sequences: | NM_018191 NP_060661.3 Q8NDN9 |
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