RBP3 / IRBP

retinol binding protein 3, interstitial

Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.

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ELISA Kits (6)

Type

Development Kit (2)

Sandwich (3)

Sandwich CLIA (1)

Target

RBP3 / IRBP (6)

Reactivity

Human (5)

Mouse (1)

Product Group

DevKit DuoPlus (2)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (2)

Antibody Pair and Standard (2)

Publications

No (5)

Yes (1)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (3)

Plasma (4)

Serum (4)

Tissue Homogenates (4)

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Human RBP3 / IRBP (Sandwich ELISA) ELISA Kit - LS-F34743

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human RBP3 / IRBP (CLIA) ELISA Kit - LS-F30003

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human RBP3 / IRBP (Sandwich ELISA) ELISA Kit - LS-F7906

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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DevKit DuoPlus Mouse RBP3 / IRBP ELISA Development Kit - LS-F71548

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

31.2 - 2000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,178; 1000 Wells/$1,739

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Human RBP3 / IRBP (Sandwich ELISA) ELISA Kit - LS-F21138

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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DevKit DuoPlus Human RBP3 / IRBP ELISA Development Kit - LS-F71618

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,182; 1000 Wells/$1,747

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