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RANBPM
RAN binding protein 9
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.
| Gene Name: | RAN binding protein 9 |
| Synonyms: | RANBP9, BPM90, RAN binding protein 9, Ran-binding protein 9, RANBPM, BPM-L, Ran-binding protein M, RanBP7 |
| Target Sequences: | NM_005493 NP_005484.2 Q96S59 |
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