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RAD54B

RAD54 homolog B (S. cerevisiae)

RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.

Gene Name: RAD54 homolog B (S. cerevisiae)
Synonyms: RAD54B, RDH54, RAD54 homolog B
Target Sequences: NM_012415 NP_036547.1 Q9Y620

Publications (1)

1
Genetic Determinants of Hearing Loss Associated With Vestibular Schwannomas. Stankovic, Konstantina M.; Mrugala, Maciej M.; Martuza, Robert L.; Silver, Michael; Betensky, Rebecca A.; Nadol, Joseph B. Jr; Stemmer-Rachamimov, Anat O. Otology & Neurotology. 2009 30:661-7. (IHC-P; Human) [Full Text Article] [PubMed:19546833]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).