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RACGAP1 / MGCRACGAP

Rac GTPase activating protein 1

Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

Gene Name: Rac GTPase activating protein 1
Synonyms: RACGAP1, GTPase activating protein, ID-GAP, KIAA1478, MgcRacGAP, Protein CYK4 homolg, Male germ cell RacGap, CYK4, HsCYK-4
Target Sequences: NM_013277 NP_037409.2 Q9H0H5

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Products
Proteins (11)
Over-Expression Lysate (6)
Recombinant (5)
RACGAP1 / MGCRACGAP (11)
No (11)
GST, N-terminus (1)
His-GST (1)
Myc-DDK (Flag) (9)
Human (8)
293T Cells (3)
E. coli (1)
HEK 293 Cells (6)
Wheat Germ Extract (1)
RACGAP1 / MGCRACGAP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RACGAP1 / MGCRACGAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
70.8 kDa
100 µg/$494
RACGAP1 / MGCRACGAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
70.8 kDa
100 µg/$494
RACGAP1 / MGCRACGAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
70.8 kDa
100 µg/$494
RACGAP1 / MGCRACGAP Protein - Recombinant Rac-GTPase Activating Protein 1 By SDS-PAGE
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E. coli
His-GST
78.1 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
RACGAP1 / MGCRACGAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
70.8 kDa
20 µg/$150
RACGAP1 / MGCRACGAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
70.8 kDa
20 µg/$150
RACGAP1 / MGCRACGAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
70.8 kDa
20 µg/$150
RACGAP1 / MGCRACGAP Protein - Purified recombinant protein RACGAP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
70.8 kDa
20 µg/$1,107
RACGAP1 / MGCRACGAP Protein - Purified recombinant protein RACGAP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
70.8 kDa
20 µg/$1,107
RACGAP1 / MGCRACGAP Protein - Purified recombinant protein RACGAP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
70.8 kDa
20 µg/$1,107
Viewing 1-11 of 11 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).