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Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
Gene Name: | kinesin family member 20A |
Synonyms: | KIF20A, Kinesin family member 20A, Kinesin-like protein KIF20A, GG10_2, Mitotic kinesin-like protein 2, MKLP2, Rabkinesin-6, RAB6KIFL |
Target Sequences: | NM_005733 NP_005724.1 O95235 |
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