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RAB22A / RAB22

RAB22A, member RAS oncogene family

Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.

Gene Name:	RAB22A, member RAS oncogene family
Family/Subfamily:	Ras GTPase superfamily IPR001806 , RAS oncogene
Synonyms:	RAB22A, GTP-binding protein RAB22A, Rab-22, RAB22, Ras-related protein Rab-22A
Target Sequences:	NM_020673 NP_065724.1 Q9UL26

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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