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RAB13

RAB13, member RAS oncogene family

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in endocytic recycling and regulates the transport to the plasma membrane of transmembrane proteins like the tight junction protein OCLN/occludin. Thereby, it regulates the assembly and the activity of tight junctions. Moreover, it may also regulate tight junction assembly by activating the PKA signaling pathway and by reorganizing the actin cytoskeleton through the activation of the downstream effectors PRKACA and MICALL2 respectively. Through its role in tight junction assembly, may play a role in the establishment of Sertoli cell barrier. Plays also a role in angiogenesis through regulation of endothelial cells chemotaxis. Also involved in neurite outgrowth. Has also been proposed to play a role in post-Golgi membrane trafficking from the TGN to the recycling endosome. Finally, it has been involved in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore may play a role in glucose homeostasis.

Gene Name: RAB13, member RAS oncogene family
Family/Subfamily: Ras GTPase superfamily IPR001806 , RAS oncogene
Synonyms: RAB13, GIG4, RAS-associated protein RAB13, Ras-related protein Rab-13
Target Sequences: NM_002870 NP_002861.1 P51153

☰ Filters
Antibodies (18)
Proteins (5)
Over-Expression Lysate (2)
Primary (18)
Recombinant (3)
RAB13 (23)
Human (17)
Mouse (12)
Rat (10)
Bat (3)
Bovine (4)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (4)
Monkey (3)
Pig (4)
Rabbit (3)
Sheep (1)
Zebrafish (3)
IHC (6)
IHC-P (3)
WB (15)
Flo (3)
ELISA (7)
IF (1)
Peptide-ELISA (2)
rabbit (14)
mouse (4)
IgG (5)
IgG1 (3)
IgG2a,k (1)
monoclonal mc (4)
polyclonal pc (14)
1600CT845.37.29 (1)
7G8A4 (1)
8E8E2 (1)
8H8 (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (15)
aa91-140 (4)
N-Terminus (1)
aa1-203 (1)
aa109-137 (1)
aa121-150 (1)
No (23)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
RAB13 Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with RAB13 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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RAB13 Rabbit anti-Human Polyclonal (aa109-137) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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RAB13 Mouse anti-Human Monoclonal (7G8A4) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
RAB13 Antibody
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RAB13 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
RAB13 Antibody - RAB13 antibody IHC-paraffin. IHC(P): Mouse Intestine Tissue.
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RAB13 Rabbit anti-Human Polyclonal (aa121-150) Antibody
Mouse, Sheep, Bovine, Rat, Pig, Horse, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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RAB13 Mouse anti-Human Monoclonal (8E8E2) Antibody
Human
ELISA, Flo
Unconjugated
100 µl/$459
RAB13 Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using RAB13 Polyclonal Antibody at dilution of 1:50(×200)
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RAB13 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
RAB13 Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using RAB13 Polyclonal Antibody at dilution of 1:50(×200)
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RAB13 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
RAB13 Antibody - RAB13 monoclonal antibody (M01), clone 8H8. Western Blot analysis of RAB13 expression in A-431.
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RAB13 Mouse anti-Human Monoclonal (8H8) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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RAB13 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$379
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RAB13 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
RAB13 Antibody - All lanes: Anti-RAB13 Antibody at 1:1000 dilution. Lane 1: MCF-7 whole cell lysate. Lane 2: A431 whole cell lysate. Lane 3: A549 whole cell lysate. Lane 4: U-87 MG whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 23 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
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RAB13 Mouse anti-Human Monoclonal (aa1-203) (1600CT845.37.29) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
RAB13 Antibody - Western blot analysis of RAB13 using COLO205 whole cells lysates
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RAB13 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RAB13 Antibody - RAB13 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAB13 Rabbit anti-Mouse Polyclonal (aa91-140) Antibody
Mouse
WB
Unconjugated
100 µl/$424
RAB13 Antibody - RAB13 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAB13 Rabbit anti-Mouse Polyclonal (aa91-140) (HRP) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Hamster, Human, Monkey, Gibbon
WB
HRP Conjugated
100 µl/$469
RAB13 Antibody - RAB13 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAB13 Rabbit anti-Mouse Polyclonal (aa91-140) (Biotin) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Hamster, Human, Monkey, Gibbon
WB
Biotin Conjugated
100 µl/$469
RAB13 Antibody - RAB13 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAB13 Rabbit anti-Mouse Polyclonal (aa91-140) (FITC) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Hamster, Human, Monkey, Gibbon
WB
FITC Conjugated
100 µl/$469
RAB13 Antibody - Western blot analysis of extracts of various cell lines, using RAB13 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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RAB13 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RAB13 Antibody
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RAB13 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
RAB13 Protein - Purified recombinant protein RAB13 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
22.6 kDa
20 µg/$1,107
RAB13 Protein - 12.5% SDS-PAGE of human RAB13 stained with Coomassie Blue
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Wheat Germ Extract
GST
48.07 kDa
10 µg/$479; 25 µg/$670
RAB13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
22.6 kDa
100 µg/$494
RAB13 Protein
Select
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Select
293T Cells
Myc-DDK (Flag)
22.6 kDa
20 µg/$150
Viewing 1-23 of 23 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).