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QPCT / QC

glutaminyl-peptide cyclotransferase

Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.

Gene Name: glutaminyl-peptide cyclotransferase
Family/Subfamily: Protease , Metallopeptidase M28
Synonyms: QPCT, EC, Glutaminyl cyclase, Glutamyl cyclase, GCT, QC, SQC
Target Sequences: NM_012413 NP_036545.1 Q16769

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
QPCT / QC (10)
No (10)
6His, N-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
His-S (1)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (2)
293T Cells (1)
Baculovirus (1)
E. coli (2)
HEK 293 Cells (2)
Mammalian Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (3)
Low endotoxin level (1)
QPCT / QC Protein - 12.5% SDS-PAGE of human QPCT stained with Coomassie Blue
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Wheat Germ Extract
GST
67.3 kDa
10 µg/$479; 25 µg/$670
QPCT / QC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
40.88 kDa
100 µg/$494
QPCT / QC Protein
Select
E. coli
His-SUMO
53.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
QPCT / QC Protein - Recombinant Glutaminyl Peptide Cyclotransferase By SDS-PAGE
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E. coli
His-S
45.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
QPCT / QC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
40.88 kDa
20 µg/$150
QPCT / QC Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
1 mg/$1,683; 100 µg/$499; 20 µg/$364
QPCT / QC Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Mammalian Cells
6His, N-terminus
100 µg/$1,116; 20 µg/$461; 1 mg/$3,921
QPCT / QC Protein - Purified recombinant protein QPCT was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
37.8 kDa
20 µg/$1,107
QPCT / QC Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
39.7 kDa
50 µg/$854
Viewing 1-10 of 10 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).