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PTTG1IP / PBF

pituitary tumor-transforming 1 interacting protein

The encoded protein, which directly binds to pituitary tumor-transforming protein-1 (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.

Gene Name: pituitary tumor-transforming 1 interacting protein
Synonyms: PTTG1IP, C21orf1, C21orf3, PBF, PTTG-binding factor, PTTG-binding factor precursor
Target Sequences: NM_004339 NP_004330.1 P53801

Publications (1)

1
Prognostic significance of pituitary tumour-transforming gene-binding factor (PBF) expression in papillary thyroid carcinoma. Chuen Hsueh, Jen-Der Lin, Yu-Sun Chang, Swei Hsueh, Tzu-Chieh Chao, Jau-Song Yu, Shih-Ming Jung, Ngan-Ming Tseng, Jui-Hung Sun, Shau-Yun Kuo, Shir-Hwa Ueng. Clinical endocrinology. 2013 Feburary;78:303-9. [Full Text Article] [PubMed:22888961]

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
PTTG1IP / PBF (5)
No (5)
GST (2)
His-GST (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
PTTG1IP / PBF Protein - 12.5% SDS-PAGE of human PTTG1IP stained with Coomassie Blue
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Wheat Germ Extract
GST
46.7 kDa
2 µg/$439
PTTG1IP / PBF Protein - 12.5% SDS-PAGE of human PTTG1IP stained with Coomassie Blue
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Wheat Germ Extract
GST
45.54 kDa
10 µg/$479; 25 µg/$670
PTTG1IP / PBF Protein - Recombinant Pituitary Tumor Transforming 1 Interacting Protein By SDS-PAGE
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E. coli
His-GST
37.0 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
PTTG1IP / PBF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
20.32 kDa
20 µg/$150
PTTG1IP / PBF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
20.32 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).