PTRF / CAVIN

polymerase I and transcript release factor

PTRF / CAVIN is a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

PTRF / CAVIN (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human PTRF / CAVIN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79997

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.3 kDa

Price:

20 µg/$150

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Human PTRF / CAVIN Protein (Recombinant GST) (Full Length) - LS-G37209

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

69.9 kDa

Price:

2 µg/$439

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Human PTRF / CAVIN Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67501

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.3 kDa

Price:

20 µg/$1,107

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Human PTRF / CAVIN Protein (Recombinant GST, N-terminus) (aa233-321) - LS-G63885

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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PTRF / CAVIN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101055

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.3 kDa

Price:

100 µg/$494

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