PTPRU

protein tyrosine phosphatase, receptor type, U

PTPRU is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.

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Proteins (1)

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Recombinant (1)

Target

PTPRU (1)

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Tag

His, N-Terminal (1)

Species

Human (1)

Source

E. coli (1)

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Purified (1)

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Human PTPRU Protein (Recombinant His, N-Terminal) (Arg1263-Arg1446) - LS-G133394

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

25.0kDa

Price:

10 µg/$266; 50 µg/$349; 200 µg/$692; 100 µg/$555; 1 mg/$1,709; 500 µg/$1,286; 5 mg/$2,659; 2 mg/$1,886

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