PTPRM / PTP Mu

protein tyrosine phosphatase, receptor type, M

PTPRM / PTP Mu is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

PTPRM / PTP Mu (4)

Publications

No (4)

Tag

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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PTPRM / PTP Mu Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124113

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

165.06 kDa

Price:

100 µg/$710

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Human PTPRM / PTP Mu Protein (Recombinant GST, N-terminus) (aa381-479) - LS-G59830

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PTPRM / PTP Mu Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78415

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

165.06 kDa

Price:

20 µg/$215

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Human PTPRM / PTP Mu Protein (Recombinant His-T7) (aa1197-1403) - LS-G13092

Source:

E. coli

Tag:

His-T7

Molecular Weight:

27.6 kDa

Price:

10 µg/$283; 50 µg/$457; 100 µg/$732; 200 µg/$912; 1 mg/$2,032; 500 µg/$1,567; 5 mg/$3,193; 2 mg/$2,219

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