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PTPN3

protein tyrosine phosphatase, non-receptor type 3

PTPN3 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: protein tyrosine phosphatase, non-receptor type 3
Family/Subfamily: Protein Phosphatase , NT5
Synonyms: PTPN3, PTP-H1, PTPH1
Target Sequences: NM_002829 NP_002820.3 P26045

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
PTPN3 (4)
No (4)
His-T7, N-terminus (2)
Myc-DDK (Flag) (2)
Human (2)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Purified (1)
PTPN3 Protein - Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) by SDS-PAGE
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E. coli
His-T7, N-terminus
31.3kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
PTPN3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
103.8 kDa
20 µg/$215
PTPN3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
103.8 kDa
100 µg/$710
PTPN3 Protein - Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) by SDS-PAGE
Select
E. coli
His-T7, N-terminus
26.9kDa
10 µg/$287; 50 µg/$482; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).