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Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
Gene Name: | protein tyrosine phosphatase, non-receptor type 23 |
Family/Subfamily: | Protein Phosphatase , NT9 |
Synonyms: | PTPN23, DKFZP564F0923, HD-PTP, TD14, Phosphatase td14, PTP-TD14, HDPTP, KIAA1471 |
Target Sequences: | AF290614 AAK28025.1 Q9H3S7 |
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