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PTP4A2 / PRL-2

protein tyrosine phosphatase type IVA, member 2

PTP4A2 / PRL-2 belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

Gene Name: protein tyrosine phosphatase type IVA, member 2
Family/Subfamily: Protein Phosphatase , PTP4A
Synonyms: PTP4A2, HH7-2, HH13, HU-PP-1, PRL-2, PRL2, Ptp-IV1a, PTPCAAX2, PTP(CAAXII), Ptp-IV1b, OV-1, PTP4A
Target Sequences: NM_080391 AAH70182.1 Q12974

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
PTP4A2 / PRL-2 (10)
No (10)
6His, C-terminus (2)
GST (2)
GST, N-terminus (1)
His (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (3)
Human (9)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (2)
PTP4A2 / PRL-2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PTP4A2 / PRL-2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18.9 kDa
100 µg/$494
Select
E. coli
GST
45.9 kDa
100 µg/$843
PTP4A2 / PRL-2 Protein
Select
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
20.2kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
PTP4A2 / PRL-2 Protein - Purified recombinant protein PTP4A2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
18.9 kDa
20 µg/$1,107
PTP4A2 / PRL-2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18.9 kDa
20 µg/$150
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
20.2 kDa
10 µg/$281; 50 µg/$389
PTP4A2 / PRL-2 Protein - Recombinant Protein Tyrosine Phosphatase Type IVA 2 (PTP4A2) by SDS-PAGE
Select
E. coli
His-T7, N-terminus
22.8kDa
10 µg/$267; 50 µg/$355; 200 µg/$710; 100 µg/$567; 1 mg/$1,735; 500 µg/$1,308; 5 mg/$2,687; 2 mg/$1,914
PTP4A2 / PRL-2 Protein - 12.5% SDS-PAGE of human PTP4A2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
45.5 kDa
10 µg/$479; 25 µg/$670
Viewing 1-10 of 10 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).