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The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | prostaglandin E synthase 2 |
Synonyms: | PTGES2, C9orf15, GATE-binding factor 1, GBF-1, MPGES-2, PGES2, Prostaglandin E synthase 2 |
Target Sequences: | NM_025072 NP_079348.1 Q9H7Z7 |
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