PSMB8 / LMP7

proteasome (prosome, macropain) subunit, beta type, 8

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.

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Products

Proteins (13)

Type

Over-Expression Lysate (4)

Recombinant (9)

Target

PSMB8 / LMP7 (13)

Publications

No (13)

Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His-T7 (3)

Myc-DDK (Flag) (6)

Species

Human (9)

Mouse (1)

Rat (1)

Source

293T Cells (2)

E. coli (5)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human PSMB8 / LMP7 Protein (Recombinant His) - LS-G2048

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human PSMB8 / LMP7 Protein (Recombinant His-T7) (aa75-261) - LS-G13995

Source:

E. coli

Tag:

His-T7

Molecular Weight:

24.5 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209

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PSMB8 / LMP7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106451

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.2 kDa

Price:

100 µg/$494

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PSMB8 / LMP7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116834

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.6 kDa

Price:

100 µg/$494

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Human PSMB8 / LMP7 Protein (Recombinant GST) (Full Length) - LS-G29982

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

56.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PSMB8 / LMP7 Protein (Recombinant GST, N-terminus) (aa173-272) - LS-G59788

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PSMB8 / LMP7 Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (aa73-276) - LS-G56468

Source:

E. coli

Tag:

10His-SUMO, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PSMB8 / LMP7 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66677

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.6 kDa

Price:

20 µg/$1,107

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Human PSMB8 / LMP7 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66678

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.2 kDa

Price:

20 µg/$1,107

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Human PSMB8 / LMP7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78279

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.6 kDa

Price:

20 µg/$150

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Human PSMB8 / LMP7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78280

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.2 kDa

Price:

20 µg/$150

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Mouse PSMB8 / LMP7 Protein (Recombinant His-T7) (aa75-272) - LS-G13984

Source:

E. coli

Tag:

His-T7

Molecular Weight:

25.9 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Rat PSMB8 / LMP7 Protein (Recombinant His-T7) (aa80-261) - LS-G13991

Source:

E. coli

Tag:

His-T7

Molecular Weight:

24.0 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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