PSMA7

proteasome (prosome, macropain) subunit, alpha type, 7

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

PSMA7 (7)

Publications

No (7)

Tag

GST (2)

His (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human PSMA7 Protein (Recombinant GST) (aa5-232) - LS-G22102

Source:

E. coli

Tag:

GST

Molecular Weight:

52.8 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PSMA7 Protein (Recombinant GST) (Full Length) - LS-G29973

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

53.02 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PSMA7 Protein (Recombinant His-T7) (aa3-211) - LS-G25701

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.8 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Human PSMA7 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67632

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.7 kDa

Price:

20 µg/$1,107

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Human PSMA7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80319

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.7 kDa

Price:

20 µg/$150

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PSMA7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99871

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.7 kDa

Price:

100 µg/$494

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Human PSMA7 Protein (Recombinant His) - LS-G3532

Source:

E. coli

Tag:

His

Price:

100 µg/$317; 500 µg/$526; 20 µg/$245

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