PSENEN / PEN-2

presenilin enhancer gamma secretase subunit

Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants.

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Products

ELISA Kits (4)

Type

Custom (1)

Sandwich (3)

Target

PSENEN / PEN-2 (4)

Reactivity

Human (1)

Mouse (1)

Rat (1)

Bovine (1)

Format

96-Well Strip Plate (4)

Publications

No (4)

Sample Type

Plasma (3)

Serum (3)

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Mouse PSENEN / PEN-2 (Sandwich ELISA) ELISA Kit - LS-F66750

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human PSENEN / PEN-2 (Sandwich ELISA) ELISA Kit - LS-F67027

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat PSENEN / PEN-2 (Sandwich ELISA) ELISA Kit - LS-F66939

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Bovine PSENEN / PEN-2 (Custom) ELISA Kit - LS-F66344

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Price:

1 Plate/$669

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