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PRX-1 / PRRX1

Paired Related Homeobox 1

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.

Gene Name: Paired Related Homeobox 1
Synonyms: PRRX1, AGOTC, Homeobox protein PHOX1, Paired related homeobox 1, PHOX1, PRX1, Paired mesoderm homeo box 1, PRX-1, PMX1
Target Sequences: NM_006902 NP_008833.1

Publications (1)

1
Involvement of PLAGL1/ZAC1 in hypocretin/orexin transcription. Tanaka S, Honda Y, Takaku S, Koike T, Oe S, Hirahara Y, Yoshida T, Takizawa N, Takamori Y, Kurokawa K, Kodama T, Yamada H. International journal of molecular medicine. 2019 May;43:2164-2176. [Full Text Article] [PubMed:30896835] [PMC:PMC6445593] Related Antibodies: LS-B2380.

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Proteins (9)
Over-Expression Lysate (4)
Recombinant (5)
PRX-1 / PRRX1 (9)
No (9)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (6)
Human (7)
293T Cells (2)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (2)
PRX-1 / PRRX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
24.2 kDa
100 µg/$494
PRX-1 / PRRX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
27.1 kDa
100 µg/$494
PRX-1 / PRRX1 Protein - 12.5% SDS-PAGE of human PRRX1 stained with Coomassie Blue
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Wheat Germ Extract
GST
50.8 kDa
10 µg/$479; 25 µg/$670
PRX-1 / PRRX1 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
PRX-1 / PRRX1 Protein - Purified recombinant protein PRRX1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.2 kDa
20 µg/$1,107
PRX-1 / PRRX1 Protein - Purified recombinant protein PRRX1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
27.1 kDa
20 µg/$1,107
PRX-1 / PRRX1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PRX-1 / PRRX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
24.2 kDa
20 µg/$150
PRX-1 / PRRX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
27.1 kDa
20 µg/$150
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).