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PRPF18

pre-mRNA processing factor 18

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18.

Gene Name: pre-mRNA processing factor 18
Synonyms: PRPF18, HPrp18, PRP18, PRP18 homolog, Pre-mRNA-splicing factor 18
Target Sequences: NM_003675 NP_003666.1 Q99633

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).