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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Prohibitin 2 / PHB2

prohibitin 2

Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases By similarity. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

Gene Name: prohibitin 2
Family/Subfamily: Transcription factor
Synonyms: PHB2, BCAP37, BAP, D-prohibitin, p22, Prohibitin-2, B-cell associated protein, Bap37, PNAS-141, Prohibitin 2, REA
Target Sequences: NM_007273 NP_001138303.1 Q99623

Publications (2)

1
Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein. Emerson V, Holtkotte D, Pfeiffer T, Wang IH, Schnlzer M, Kempf T, Bosch V. Journal of virology. 2010 84:1355-65. [PubMed:19906925] [PMC:PMC2812343] Related Antibodies: LS-B1889.
2
Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes. Lucas CR, Cordero-Nieves HM, Erbe RS, McAlees JW, Bhatia S, Hodes RJ, Campbell KS, Sanders VM. Journal of immunology (Baltimore, Md. : 1950). 2013 190:723-36. [PubMed:23241883] [PMC:PMC3538926] Related Antibodies: LS-B1889.

Viewing 1-25 of 44 items
Prohibitin 2 / PHB2 Antibody - Anti-PHB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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(2) Publication(s)
Rabbit Polyclonal (IgG) to Mouse Prohibitin 2 / PHB2
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
50µl   $425.00
Prohibitin 2 / PHB2 Antibody - Anti-PHB2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Rat, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
50µg   1mg/ml   $425.00
Prohibitin 2 / PHB2 Antibody - Human, Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal to Human Prohibitin 2 / PHB2
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200µl   $425.00
Prohibitin 2 / PHB2 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ICC, IHC, IHC-P, WB
Unconjugated
100µl   0.66mg/ml   $485.00
Prohibitin 2 / PHB2 Antibody - Prohibitin 2 / PHB2 antibody. IHC(P): Human Lung Cancer Tissue.
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Rabbit Polyclonal to Human Prohibitin 2 / PHB2
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100µg   200µl   0.5mg/ml   $355.00
Prohibitin 2 / PHB2 Antibody - PHB2 Antibody (Y248)immunohistochemistry of formalin-fixed and paraffin-embedded human prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Human Prohibitin 2 / PHB2
Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Prohibitin 2 / PHB2 Antibody - Detection of Human REA by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-REA used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
IHC, IHC-P, IP
Unconjugated
100µl   1mg/ml   $395.00
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg   $335.00
Prohibitin 2 / PHB2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $285.00; 100µl   $385.00
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Rabbit Polyclonal to Human Prohibitin 2 / PHB2
Human
ICC, IF, WB
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, IHC, WB
FITC Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
Prohibitin 2 / PHB2 Antibody - Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PHB2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Rabbit Polyclonal to Human Prohibitin 2 / PHB2
Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Prohibitin 2 / PHB2 Antibody
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Rabbit Polyclonal to Human Prohibitin 2 / PHB2
Human
IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $275.00
Select
Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Mouse, Rat, Human
IHC, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Rabbit Polyclonal to Human Prohibitin 2 / PHB2
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Sheep Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Rabbit, Mouse, Human
ELISA, WB
Unconjugated
100µg   $770.00
Select
Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Mouse, Human
IP, WB
Unconjugated
100µl   0.2mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human Prohibitin 2 / PHB2
Mouse, Human
IP, WB
Unconjugated
100µl   0.2mg/ml   $395.00

Viewing 1-25 of 44 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).