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Unfortunately, the antibody (ID:159045) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



PRKCE / PKC-Epsilon

protein kinase C, epsilon

Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration. In HeLa cells, contributes to hepatocyte growth factor (HGF)-induced cell migration, and in human corneal epithelial cells, plays a critical role in wound healing after activation by HGF. During cytokinesis, forms a complex with YWHAB, which is crucial for daughter cell separation, and facilitates abscission by a mechanism which may implicate the regulation of RHOA. In cardiac myocytes, regulates myofilament function and excitation coupling at the Z-lines, where it is indirectly associated with F-actin via interaction with COPB1. During endothelin-induced cardiomyocyte hypertrophy, mediates activation of PTK2/FAK, which is critical for cardiomyocyte survival and regulation of sarcomere length. Plays a role in the pathogenesis of dilated cardiomyopathy via persistent phosphorylation of troponin I (TNNI3). Involved in nerve growth factor (NFG)-induced neurite outgrowth and neuron morphological change independently of its kinase activity, by inhibition of RHOA pathway, activation of CDC42 and cytoskeletal rearrangement. May be involved in presynaptic facilitation by mediating phorbol ester-induced synaptic potentiation. Phosphorylates gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2), which reduces the response of GABA receptors to ethanol and benzodiazepines and may mediate acute tolerance to the intoxicating effects of ethanol. Upon PMA treatment, phosphorylates the capsaicin- and heat-activated cation channel TRPV1, which is required for bradykinin-induced sensitization of the heat response in nociceptive neurons. Is able to form a complex with PDLIM5 and N-type calcium channel, and may enhance channel activities and potentiates fast synaptic transmission by phosphorylating the pore-forming alpha subunit CACNA1B (CaV2.2). In prostate cancer cells, interacts with and phosphorylates STAT3, which increases DNA-binding and transcriptional activity of STAT3 and seems to be essential for prostate cancer cell invasion. Downstream of TLR4, plays an important role in the lipopolysaccharide (LPS)-induced immune response by phosphorylating and activating TICAM2/TRAM, which in turn activates the transcription factor IRF3 and subsequent cytokines production. In differentiating erythroid progenitors, is regulated by EPO and controls the protection against the TNFSF10/TRAIL-mediated apoptosis, via BCL2. May be involved in the regulation of the insulin-induced phosphorylation and activation of AKT1.

Gene Name: protein kinase C, epsilon
Family/Subfamily: Protein Kinase , PKC
Synonyms: PRKCE, NPKC-epsilon, PKC epsilon, Protein kinase C epsilon, Protein kinase C epsilon type, Pkcepsilon, PKCE, Protein kinase C, epsilon
Target Sequences: NM_005400 NP_005391.1 Q02156

Filtered By: None
Target
prkce-pkc-epsilon (61)
Reactivity
Human (50)
Mouse (33)
Rat (25)
Bat (3)
Bovine (3)
Dog (8)
Guinea pig (1)
Hamster (3)
Mammal (2)
Monkey (6)
Pig (2)
Rabbit (4)
Rodent (1)
Application
IHC (18)
IHC-Fr (2)
IHC-P (12)
WB (57)
Flo (11)
ELISA (28)
ICC (3)
IF (10)
IP (7)
RIA (1)
Host
rabbit (49)
mouse (11)
sheep (1)
Isotype
IgG (40)
IgG1 (6)
IgG2a (1)
IgG2b (4)
Clonality
monoclonal mc (12)
polyclonal pc (49)
Clone
1B4 (1)
1B7 (1)
1G5 (1)
22B10 (1)
2A12 (1)
2E9 (1)
3A12 (1)
3F10 (1)
4B3 (1)
4D12 (1)
4G8 (1)
I27-K (1)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (4)
FITC Conjugated (5)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (40)
Epitope
N-Terminus (7)
aa122-150 (7)
C-Terminus (5)
aa403-672 (3)
pSer729 (3)
aa726-737 (2)
Internal (1)
Phe725 (1)
aa123-150 (1)
aa206-236 (1)
aa488-737 (1)
aa53-236 (1)
aa580-737 (1)
aa670-750 (1)
aa688-737 (1)
aa721-737 (1)
Publications
No (61)
Showing 1-25 out of 61 results
Anti-PRKCE / PKC-Epsilon Antibody IHC-plus™ LS-B7150

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Mouse, Rat, Human
IHC-P WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 2A12) LS-C172682

Mouse Monoclonal [clone 2A12] (IgG2b) to Human PRKCE / PKC-Epsilon
Dog, Human, Monkey
Flo IF IHC-P WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (aa726-737) LS-C152735

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC IP WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 4G8) LS-C337258

Mouse Monoclonal [clone 4G8] (IgG2b) to Human PRKCE / PKC-Epsilon
Human, Monkey
Flo IF IHC-P WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 4B3) LS-C172684

Mouse Monoclonal [clone 4B3] (IgG2b) to Human PRKCE / PKC-Epsilon
Dog, Human, Monkey
Flo IF IHC-P WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 1B4) LS-C172674

Mouse Monoclonal [clone 1B4] (IgG2b) to Human PRKCE / PKC-Epsilon
Dog, Human, Monkey
Flo IF IHC-P WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 22B10) LS-C75178

Rabbit Monoclonal [clone 22B10] (IgG) to Human PRKCE / PKC-Epsilon
Mouse, Rat, Human
WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 1B7) LS-C172661

Mouse Monoclonal [clone 1B7] (IgG1) to Human PRKCE / PKC-Epsilon
Dog, Human, Monkey
Flo IF IHC-P
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 2E9) LS-C172683

Mouse Monoclonal [clone 2E9] (IgG1) to Human PRKCE / PKC-Epsilon
Dog, Human, Monkey
Flo IF WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody LS-C331903

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Mouse, Rat, Human
ICC IHC WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 3F10) LS-C172606

Mouse Monoclonal [clone 3F10] (IgG1) to Human PRKCE / PKC-Epsilon
Human
Flo IF WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 4D12) LS-C172605

Mouse Monoclonal [clone 4D12] (IgG1) to Human PRKCE / PKC-Epsilon
Human
Flo IF WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (clone 3A12) LS-C172750

Mouse Monoclonal [clone 3A12] (IgG1) to Human PRKCE / PKC-Epsilon
Human
Flo IHC-P WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (aa688-737) IHC-plus™ LS-B13267

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Mouse, Rat, Human
ELISA IHC-P WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody LS-C401340

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (C-Terminus) LS-C368477

Rabbit Polyclonal to Human PRKCE / PKC-Epsilon
Rabbit, Mouse, Rat, Human
ICC IF WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody LS-C38540

Rabbit Polyclonal to Human PRKCE / PKC-Epsilon
Human
ELISA IF WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (C-Terminus) LS-C26191

Rabbit Polyclonal (IgG) to Rat PRKCE / PKC-Epsilon
Rat, Mammal
ELISA ICC IHC-Fr IHC-P WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (N-Terminus) LS-C328351

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Human
ELISA IHC WB
Unconjugated
Anti-PRKCE / PKC-Epsilon Antibody (N-Terminus, Biotin) LS-C281423

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Human
ELISA IHC WB
Biotin Conjugated
Anti-PRKCE / PKC-Epsilon Antibody (N-Terminus, FITC) LS-C281424

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Human
ELISA IHC WB
FITC Conjugated
Anti-PRKCE / PKC-Epsilon Antibody (N-Terminus, AP) LS-C281421

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Human
ELISA IHC WB
AP Conjugated
Anti-PRKCE / PKC-Epsilon Antibody (N-Terminus, Azide-free, HRP) LS-C281425

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Human
ELISA IHC WB
HRP Conjugated, Azide-free
Anti-PRKCE / PKC-Epsilon Antibody (N-Terminus, PE) LS-C281427

Rabbit Polyclonal (IgG) to Human PRKCE / PKC-Epsilon
Human
ELISA IHC WB
PE Conjugated
Anti-PRKCE / PKC-Epsilon Antibody (AP) LS-C510874

Rabbit Polyclonal (IgG) to Mouse PRKCE / PKC-Epsilon
Mouse, Rat, Human
IHC IP WB
AP Conjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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