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PRDX6 / Peroxiredoxin 6

peroxiredoxin 6

Involved in redox regulation of the cell. Can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Gene Name:	peroxiredoxin 6
Synonyms:	PRDX6, 24 kDa protein, 1-Cys, 1-Cys peroxiredoxin, 1-Cys PRX, AOP2, Antioxidant protein 2, AiPLA2, KIAA0106, Liver 2D page spot 40, NSGPx, p29, Peroxiredoxin 6, Peroxiredoxin-6, Red blood cells page spot 12
Target Sequences:	NM_004905 NP_004896.1 P30041

Publications (3)

Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation. Chhunchha B, Kubo E, Fatma N, Singh DP. Cell death & disease. 2017 8:e2525. (WB; Human) [Full Text Article] [PubMed:28055018] [PMC:PMC5386354] Related Antibodies: LS-B6255.

Extracellular Vesicles from Human Papilloma Virus-Infected Cervical Cancer Cells Enhance HIV-1 Replication in Differentiated U1 Cell Line. Sabina Ranjit, Sunitha Kodidela, Namita Sinha, Subhash Chauhan, Santosh Kumar. Viruses. 2020 Feb;12:239. [Full Text Article] [PubMed:32098055] [PMC:PMC7077309] Related Antibodies: LS-C162131.

Engineered Sumoylation-Deficient Prdx6 Mutant Protein-Loaded Nanoparticles Provide Increased Cellular Defense and Prevent Lens Opacity. Bhavana Chhunchha, Eri Kubo, Uday B Kompella, Dhirendra P Singh. Antioxidants. 2021 Aug;10:1245. [Full Text Article] [PubMed:34439493] [PMC:PMC8389307]

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