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PRDX2 / Peroxiredoxin 2

peroxiredoxin 2

PRDX2 / Peroxiredoxin 2 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Gene Name: peroxiredoxin 2
Synonyms: PRDX2, NKEF-B, Peroxiredoxin 2, PrP, TDPX1, Thiol-specific antioxidant 1, TPX1, NKEFB, PRXII, Thiol-specific antioxidant, Torin, Peroxiredoxin-2, PRX2, PTX1, Thioredoxin peroxidase 1, TSA
Target Sequences: NM_005809 NP_005800.3 P32119

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).