PRDM5

PR domain containing 5

Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells.

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Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

PRDM5 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PRDM5 Protein (Recombinant GST) (Full Length) - LS-G32506

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

39.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PRDM5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85182

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

72.9 kDa

Price:

20 µg/$215

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PRDM5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111574

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

72.9 kDa

Price:

100 µg/$710

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