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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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PRCC / RCCP1
papillary renal cell carcinoma (translocation-associated)
PRCC / RCCP1 is a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.
| Gene Name: | papillary renal cell carcinoma (translocation-associated) |
| Synonyms: | PRCC, Proline-rich protein PRCC, RCCP1, TPRC |
| Target Sequences: | NM_005973 NP_005964.3 Q92733 |
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