PRAME

preferentially expressed antigen in melanoma

PRAME encodes a 509 amino acid antigen, lacking a signal sequence, and recognized on a human melanoma cell line by a T-lymphocyte clone. A significant level of PRAME mRNA is detected in normal testis as well as in many melanomas, non-small cell lung carcinomas, sarcomas, head and neck tumors and renal carcinomas. PRAME is expressed predominantly in acute leukemias carrying chromosomal abnormalities such as translocation t(8:21), which fuses the AML1 and ETO genes. PRAME expression shares several characteristics with the expression patterns of MAGE, BAGE, and GAGE gene families, all of which are expressed in tumors. PRAME is expressed in a higher proportion of samples than genes of the MAGE, BAGE, and GAGE families, and of these four groups, only PRAME is expressed by acute myeloid leukemias.

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Proteins (16)

Type

Over-Expression Lysate (10)

Recombinant (6)

Target

PRAME (16)

Publications

No (16)

Tag

6His, N-terminus (1)

GST (1)

His (2)

His-GST (1)

Myc-DDK (Flag) (11)

Species

Human (11)

Source

293T Cells (5)

E. coli (3)

HEK 293 Cells (6)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

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Human PRAME Protein (Recombinant His) (Full Length) - LS-G23082

Source:

Yeast

Tag:

His

Molecular Weight:

59.9 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human PRAME Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G21074

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

62 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PRAME Protein (Recombinant GST) (Full Length) - LS-G32875

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

81.73 kDa

Price:

2 µg/$439

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Human PRAME Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66637

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

20 µg/$1,107

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Human PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78157

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

20 µg/$150

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Human PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78158

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

20 µg/$150

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Human PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78160

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

20 µg/$215

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Human PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78161

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

20 µg/$150

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Human PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78162

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

20 µg/$150

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PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102972

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

100 µg/$494

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PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102973

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

100 µg/$710

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PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102974

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

100 µg/$494

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PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102975

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

100 µg/$494

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PRAME Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100731

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

100 µg/$494

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Human PRAME Protein (Recombinant His-GST) (aa416-502) - LS-G15849

Source:

E. coli

Tag:

His-GST

Molecular Weight:

36.9 kDa

Price:

10 µg/$287; 50 µg/$477; 100 µg/$762; 200 µg/$952; 1 mg/$2,083; 500 µg/$1,613; 5 mg/$3,333; 2 mg/$2,272

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Human PRAME Protein (Recombinant His) (aa416-502) - LS-G15856

Source:

E. coli

Tag:

His

Molecular Weight:

11.4 kDa

Price:

10 µg/$287; 50 µg/$477; 100 µg/$762; 200 µg/$952; 1 mg/$2,083; 500 µg/$1,613; 5 mg/$3,333; 2 mg/$2,272

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