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PPP4R1 / PP4R1 is one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.
Gene Name: | protein phosphatase 4, regulatory subunit 1 |
Synonyms: | PPP4R1, MEG1, PP4R1, PP4(Rmeg), Serine/threonine phosphatase 4 |
Target Sequences: | NM_005134 NP_005125.1 |
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