PPP2R4

protein phosphatase 2A activator, regulatory subunit 4

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg2+ (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg2+ (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.

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Products

Proteins (18)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (10)

Recombinant (7)

Target

PPP2R4 (18)

Publications

No (18)

Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

6His, N-terminus (2)

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (11)

Species

Human (13)

Rat (1)

Source

293T Cells (5)

E. coli (3)

HEK 293 Cells (8)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human PPP2R4 Protein (Recombinant GST) (Full Length) - LS-G29859

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.2 kDa

Price:

10 µg/$479; 25 µg/$670

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PPP2R4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110759

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

100 µg/$494

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PPP2R4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104785

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

100 µg/$494

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PPP2R4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104787

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.7 kDa

Price:

100 µg/$494

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PPP2R4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104786

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.5 kDa

Price:

100 µg/$494

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Rat PPP2R4 Protein (Recombinant His-T7) (aa1-323) - LS-G25405

Source:

E. coli

Tag:

His-T7

Molecular Weight:

40.3 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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Human PPP2R4 Protein (Over-Expression Lysate 6His, N-terminus) (Ala2-Gly323) - LS-G26769

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

40 kDa

Price:

100 µg/$298

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Human PPP2R4 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Ala2-Gly323) - LS-G26916

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

40 kDa

Price:

200 µl/$283

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Human PPP2R4 Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (aa2-358) - LS-G56717

Source:

E. coli

Tag:

10His-SUMO, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PPP2R4 Protein (Recombinant GST, N-terminus) (aa21-120) - LS-G59698

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PPP2R4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66586

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

20 µg/$1,107

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Human PPP2R4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66587

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

20 µg/$1,107

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Human PPP2R4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78048

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

20 µg/$150

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Human PPP2R4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78050

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.5 kDa

Price:

20 µg/$150

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Human PPP2R4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78049

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

20 µg/$150

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Human PPP2R4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78052

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

20 µg/$150

Select

Human PPP2R4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78053

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.7 kDa

Price:

20 µg/$150

Select

Human PPP2R4 Protein (Recombinant His, N-Terminal) (Ala2-Gly323) - LS-G96894

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

39 kDa

Price:

10 µg/$265; 100 µg/$365; 50 µg/$315

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