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Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid.
Gene Name: | phosphatidic acid phosphatase type 2 domain containing 2 |
Synonyms: | PPAPDC2, BA6J24.6, PSDP |
Target Sequences: | NM_203453 NP_982278.3 Q8IY26 |
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