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PPAN

peter pan homolog (Drosophila)

PPAN is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.

Gene Name: peter pan homolog (Drosophila)
Synonyms: PPAN, BXDC3, Peter Pan homolog, SSF, SSF2, Peter pan (Drosophila) homolog, Second-step splicing factor 1, Suppressor of sterile four 1, Suppressor of SWI4 1 homolog, Homolog of S. cerevisiae SSF1, Peter pan homolog (Drosophila), SSF-1, SSF1
Target Sequences: NM_020230 NP_064615.3 Q9NQ55

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Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
PPAN (6)
No (6)
GST, N-terminus + His, C-terminus (1)
His (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Yeast (1)
PPAN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
87.7 kDa
100 µg/$710
PPAN Protein
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E. coli
GST, N-terminus + His, C-terminus
79 kDa
50 µg/$419
PPAN Protein
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Yeast
His
55.12 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
PPAN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
87.7 kDa
20 µg/$215
PPAN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
53 kDa
20 µg/$150
PPAN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
53 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).