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PNPLA6 / NTE

patatin-like phospholipase domain containing 6

PNPLA6 is a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: patatin-like phospholipase domain containing 6
Synonyms: PNPLA6, IPLA2delta, Sws, Neuropathy target esterase, NTEMND, SPG39, NTE
Target Sequences: NM_006702 NP_006693.3 Q8IY17

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
PNPLA6 / NTE (5)
No (5)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (3)
Rat (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
PNPLA6 / NTE Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PNPLA6 / NTE Protein - Recombinant  Neuropathy Target Esterase By SDS-PAGE
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E. coli
His
22.5 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
PNPLA6 / NTE Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
150.8 kDa
100 µg/$710
PNPLA6 / NTE Protein - Purified recombinant protein PNPLA6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
150.8 kDa
20 µg/$1,107
PNPLA6 / NTE Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
150.8 kDa
20 µg/$215
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).