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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PNPLA6 / NTE

patatin-like phospholipase domain containing 6

PNPLA6 is a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: patatin-like phospholipase domain containing 6
Synonyms: PNPLA6, IPLA2delta, Sws, Neuropathy target esterase, NTEMND, SPG39, NTE
Target Sequences: NM_006702 NP_006693.3 Q8IY17

Filtered By: None
Target
PNPLA6 / NTE (39)
Reactivity
Human (24)
Mouse (9)
Rat (16)
Bat (4)
Bovine (5)
Fish (3)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (4)
Orangutan (3)
Pig (5)
Rabbit (4)
Zebrafish (5)
Application
IHC (14)
IHC-Fr (3)
IHC-P (6)
WB (34)
ELISA (14)
ICC (2)
IF (2)
IP (3)
Peptide-ELISA (1)
Host
rabbit (37)
mouse (1)
goat (1)
Isotype
IgG (28)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (38)
Clone
3D10 (1)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (4)
Magnetic beads Conjugated (1)
PE Conjugated (2)
Sepharose Conjugated (1)
Unconjugated (16)
Epitope
aa965-1137 (10)
aa1000-1029 (8)
C-Terminus (7)
1031-1080 aa, Internal (1)
80-160 aa, N-terminal (1)
N-Terminus (1)
aa1317-1342 (1)
aa1323-1348 (1)
aa496-510 (1)
Publications
No (39)
Showing 1-25 of 39 results

PNPLA6 / NTE Antibody (1031-1080 aa, Internal) LS-C387118
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Mouse, Rat, Human
ELISA IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $265.00
Immunohistochemistry of NTE antibody
Immunohistochemistry of NTE antibody
Immunohistochemistry of NTE antibody
Immunohistochemistry of NTE antibody

PNPLA6 / NTE Antibody LS-C671712
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Human
ELISA IF IHC IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image at a dilution of 1:500 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of Hela cells at a dilution of 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .
Immunohistochemistry image at a dilution of 1:500 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of Hela cells at a dilution of 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .

PNPLA6 / NTE Antibody (clone 3D10) LS-C134033
Mouse Monoclonal [clone 3D10] (IgG2a,k) to Human PNPLA6 / NTE
Human
ELISA IHC IHC-P WB
Unconjugated
100µg  $355.00
Immunoperoxidase of monoclonal antibody to PNPLA6 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
Detection limit for recombinant GST tagged PNPLA6 is 1 ng/ml as a capture antibody.
Immunoperoxidase of monoclonal antibody to PNPLA6 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
Detection limit for recombinant GST tagged PNPLA6 is 1 ng/ml as a capture antibody.

PNPLA6 / NTE Antibody LS-C753070
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Human
ELISA IF IP WB
Unconjugated
100µg  $335.00

PNPLA6 / NTE Antibody (aa1323-1348) LS-C122327
Rabbit Polyclonal (IgG) to Zebrafish PNPLA6 / NTE
Zebrafish
IHC IHC-Fr IHC-P WB
Unconjugated
100µg  $530.00

PNPLA6 / NTE Antibody (aa1317-1342) LS-C388977
Rabbit Polyclonal (IgG) to Zebrafish PNPLA6 / NTE
Zebrafish
IHC IHC-Fr IHC-P WB
Unconjugated
100µg 0.2mg/ml  $415.00
Western blot testing of NTE antibody and Lane 1: Male Zebrafish; 2: Female Zebrafish; Predicted size: 110KD; Observed size: 110KD
Western blot testing of NTE antibody and Lane 1: Male Zebrafish; 2: Female Zebrafish; Predicted size: 110KD; Observed size: 110KD

PNPLA6 / NTE Antibody (C-Terminus) LS-C172019
Rabbit Polyclonal to Fish PNPLA6 / NTE
Fish, Zebrafish
IHC IHC-Fr IHC-P WB
Unconjugated
100µg  $295.00
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
 This image was taken for the unconjugated form of this product. Other forms have not been tested.

PNPLA6 / NTE Antibody (aa1000-1029) LS-C324144
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Human
ELISA WB
Unconjugated
200µl  $530.00

PNPLA6 / NTE Antibody (aa1000-1029, Biotin) LS-C266664
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

PNPLA6 / NTE Antibody (aa1000-1029, FITC) LS-C266665
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Human
ELISA WB
FITC Conjugated
200µl  $680.00

PNPLA6 / NTE Antibody (aa1000-1029, APC) LS-C266663
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Human
ELISA WB
APC Conjugated
200µl  $680.00

PNPLA6 / NTE Antibody (aa1000-1029, PE) LS-C266667
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Human
ELISA WB
PE Conjugated
200µl  $680.00

PNPLA6 / NTE Antibody (aa1000-1029, AP) LS-C266662
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Human
ELISA WB
AP Conjugated
200µl  $680.00

PNPLA6 / NTE Antibody (aa1000-1029, Azide-free, HRP) LS-C266666
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

PNPLA6 / NTE Antibody LS-C742687
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Mouse, Human
ELISA WB
Unconjugated
50µg 1mg/ml  $265.00; 100µg 1mg/ml  $325.00

PNPLA6 / NTE Antibody (80-160 aa, N-terminal) LS-C384978
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Mouse, Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of NTE antibody
Western blot of NTE antibody

PNPLA6 / NTE Antibody LS-C742895
Rabbit Polyclonal (IgG) to Human PNPLA6 / NTE
Mouse, Rat, Human
ELISA WB
Unconjugated
50µg 1mg/ml  $265.00; 100µg 1mg/ml  $325.00
Western blot analysis of lysate from AD293 cells, using PNPLA6 Antibody.
Western blot analysis of lysate from AD293 cells, using PNPLA6 Antibody.

PNPLA6 / NTE Antibody (aa965-1137) LS-C373584
Rabbit Polyclonal (IgG) to Rat PNPLA6 / NTE
Rat
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $575.00; 10ml 0.5mg/ml  $2,280.00
Western blot of PNPLA6 antibody.
Western blot of PNPLA6 antibody.

PNPLA6 / NTE Antibody (aa965-1137, HRP) LS-C713930
Rabbit Polyclonal (IgG) to Rat PNPLA6 / NTE
Rat
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $355.00; 1ml  $740.00; 10ml  $2,955.00
Western blot of PNPLA6 antibody.
Western blot of PNPLA6 antibody.

PNPLA6 / NTE Antibody (aa965-1137, Biotin) LS-C688986
Rabbit Polyclonal (IgG) to Rat PNPLA6 / NTE
Rat
IHC WB
Biotin Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $620.00; 10ml  $2,505.00
Western blot of PNPLA6 antibody.
Western blot of PNPLA6 antibody.

PNPLA6 / NTE Antibody (aa965-1137, Biotin) LS-C424417
Rabbit Polyclonal (IgG) to Rat PNPLA6 / NTE
Rat
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $385.00

PNPLA6 / NTE Antibody (aa965-1137, FITC) LS-C424507
Rabbit Polyclonal (IgG) to Rat PNPLA6 / NTE
Rat
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $415.00

PNPLA6 / NTE Antibody (aa965-1137, PE) LS-C728003
Rabbit Polyclonal (IgG) to Rat PNPLA6 / NTE
Rat
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $345.00; 1ml  $680.00; 10ml  $2,730.00
Western blot of PNPLA6 antibody.
Western blot of PNPLA6 antibody.

PNPLA6 / NTE Antibody (aa965-1137, Cy3) LS-C704922
Rabbit Polyclonal (IgG) to Rat PNPLA6 / NTE
Rat
IHC WB
Cy3 Conjugated
20µl  $255.00; 100µl  $375.00; 200µl  $465.00; 1ml  $1,140.00; 10ml  $4,560.00
Western blot of PNPLA6 antibody.
Western blot of PNPLA6 antibody.

PNPLA6 / NTE Antibody (C-Terminus) LS-C135198
Rabbit Polyclonal to Mouse PNPLA6 / NTE
Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
PNPLA6 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PNPLA6 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 39 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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