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May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.Isoform 1 has no prospholipid scramblase activity, due to the lack of a N-terminal proline-rich domain.
Gene Name: | phospholipid scramblase 2 |
Synonyms: | PLSCR2, PL scramblase 2, Phospholipid scramblase 2 |
Target Sequences: | Q9NRY7 Q9NRY7 |
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