PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

PLOD2 is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

PLOD2 (6)

Publications

No (6)

Tag

GST (2)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human PLOD2 Protein (Recombinant GST) (Full Length) - LS-G29773

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

106.26 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PLOD2 Protein (Recombinant His) (aa644-737) - LS-G25450

Source:

E. coli

Tag:

His

Molecular Weight:

14.3 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human PLOD2 Protein (Recombinant GST) (Full Length) - LS-G29772

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

109.12 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PLOD2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66209

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.4 kDa

Price:

20 µg/$1,107

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Human PLOD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77171

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.4 kDa

Price:

20 µg/$150

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PLOD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102535

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.4 kDa

Price:

100 µg/$494

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