PLEKHO1 / CKIP-1

pleckstrin homology domain containing, family O member 1

Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.

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Products

Antibodies (13)

Type

Primary (13)

Target

PLEKHO1 / CKIP-1 (13)

Reactivity

Human (13)

Mouse (2)

Rat (2)

Chimpanzee (3)

Gibbon (3)

Monkey (3)

Application

IHC (4)

IHC-P (3)

WB (8)

Flo (1)

ELISA (8)

IF (1)

Host

rabbit (12)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (7)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (12)

Clone

1C7 (1)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (7)

Epitope

N-Terminus (4)

aa49-77 (1)

Publications

No (13)

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IHC-plus™ PLEKHO1 / CKIP-1 Antibody LS-B5042

(4.0) Rating

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$545

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PLEKHO1 / CKIP-1 Antibody LS-C401532

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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PLEKHO1 / CKIP-1 Antibody LS-C500859

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PLEKHO1 / CKIP-1 Antibody (HRP) LS-C501019

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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PLEKHO1 / CKIP-1 Antibody (Biotin) LS-C501017

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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PLEKHO1 / CKIP-1 Antibody (FITC) LS-C501016

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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PLEKHO1 / CKIP-1 Antibody (N-Terminus) LS-C116343

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PLEKHO1 / CKIP-1 Antibody (N-Terminus, HRP) LS-C450497

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PLEKHO1 / CKIP-1 Antibody (N-Terminus, Biotin) LS-C450495

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PLEKHO1 / CKIP-1 Antibody (N-Terminus, FITC) LS-C450496

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PLEKHO1 / CKIP-1 Antibody (aa49-77) LS-C168797

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal (aa49-77) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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PLEKHO1 / CKIP-1 Antibody (clone 1C7) LS-C134065

Antibody:

PLEKHO1 / CKIP-1 Mouse anti-Human Monoclonal (1C7) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µg/$423

Select

PLEKHO1 / CKIP-1 Antibody LS-C753736

Antibody:

PLEKHO1 / CKIP-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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