PLEKHA8

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8

Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.

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Products

Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

PLEKHA8 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus + His, C-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (4)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PLEKHA8 Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G145177

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

77.3 kDa

Price:

50 µg/$419

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Human PLEKHA8 Protein (Recombinant GST) (Full Length) - LS-G35816

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

75.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PLEKHA8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84413

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.3 kDa

Price:

20 µg/$150

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Human PLEKHA8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84412

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

20 µg/$150

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PLEKHA8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102067

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.3 kDa

Price:

100 µg/$494

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PLEKHA8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G130964

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

100 µg/$494

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