PLCG1

phospholipase C, gamma 1

PLCG1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

PLCG1 (7)

Publications

No (7)

Tag

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (1)

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PLCG1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104133

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

148.4 kDa

Price:

100 µg/$710

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PLCG1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117834

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

148.5 kDa

Price:

100 µg/$710

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Human PLCG1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G73972

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

148.5 kDa

Price:

20 µg/$215

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Human PLCG1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G73981

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

148.4 kDa

Price:

20 µg/$215

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Human PLCG1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64696

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

148.5 kDa

Price:

20 µg/$1,107

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Human PLCG1 Protein (Recombinant GST, N-terminus) (aa1192-1291) - LS-G59634

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PLCG1 Protein (Recombinant His-T7) (aa1091-1290) - LS-G11897

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.6 kDa

Price:

10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113

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