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Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position with a preference for arachidonoyl phospholipids. Has a much weaker activity than PLA2G4A. Isoform 3 has calcium-dependent activity against palmitoyl-arachidonyl-phosphatidylethanolamine and low level lysophospholipase activity but no activity against phosphatidylcholine. Isoform 5 does have activity against phosphatidylcholine.
Gene Name: | phospholipase A2, group IVB (cytosolic) |
Synonyms: | PLA2G4B, CPLA2-BETA, HsT16992, Phospholipase A2 group IVB |
Target Sequences: | P0C869 P0C869 |
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