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Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue By similarity. N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.
Gene Name: | phospholipase A2, group XVI |
Synonyms: | PLA2G16, AdPLA, Adipose-specific PLA2, Group XVI phospholipase A1/A2, Group XVI phospholipase A2, H-REV107-1, HRAS-like suppressor 3, HRASLS3, HREV107-3, HRAS-like suppressor 1, HREV107-1, H-rev 107 protein homolog, HREV107, HRSL3, Phospholipase A2, group XVI |
Target Sequences: | NM_007069 NP_009000.2 P53816 |
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