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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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PLA2G15 / ACS
phospholipase A2, group XV
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.
| Gene Name: | phospholipase A2, group XV |
| Family/Subfamily: | Phospholipase , not assigned-Phospholipase |
| Synonyms: | PLA2G15, 1-O-acylceramide synthase, ACS, Group XV phospholipase A2, GXVPLA2, LCAT-like lysophospholipase, LYPLA3, Lysosomal phospholipase A2, Phospholipase A2, group XV, LLPL, LPLA2, Lysophospholipase 3 |
| Target Sequences: | NM_012320 NP_036452.1 Q8NCC3 |
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