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PKLR

pyruvate kinase, liver and RBC

PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: pyruvate kinase, liver and RBC
Synonyms: PKLR, PKL, Pyruvate kinase, liver and RBC, Pyruvate kinase type L, Red cell/liver pyruvate kinase, RPK, PK1, PKR, Pyruvate kinase 1, Pyruvate kinase isozymes R/L, R-type/L-type pyruvate kinase, PKRL, Pyruvate kinase isozyme R/L
Target Sequences: NM_000298 NP_000289.1 P30613

Publications (1)

1
Proteomic analyses of transgenic LQT1 and LQT2 rabbit hearts elucidate an increase in expression and activity of energy producing enzymes. Jindal HK, Merchant E, Balschi JA, Zhangand Y, Koren G. Journal of proteomics. 2012 75:5254-65. (WB; Rabbit) [PubMed:22796357]

☰ Filters
Products
ELISA Kits (15)
Competitive EIA (1)
Custom (3)
Sandwich (9)
Sandwich CLIA (2)
PKLR (15)
Human (5)
Mouse (3)
Rat (6)
Dog (1)
12 x 8-Well Microstrips (2)
96-Well Microplate (2)
96-Well Strip Plate (11)
No (15)
Cell Lysates (1)
Plasma (11)
Serum (11)
Tissue Homogenates (5)
PKLR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
39.06 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$764
PKLR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3.12 - 200 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PKLR ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PKLR ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
PKLR ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
PKLR ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
PKLR ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.156 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
PKLR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PKLR ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Rat
0.156 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
PKLR ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PKLR ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
5 - 100 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
PKLR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PKLR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PKLR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
PKLR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
Viewing 1-15 of 15 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).