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Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.
Gene Name: | phosphatidylinositol transfer protein, membrane-associated 1 |
Synonyms: | PITPNM1, DRES9, NIR2, NIR-2, PITPNM, PITPnm 1, RDGBA, RDGB, RDGB1, Retinal degeneration B alpha 1, Rd9, RDGBA1 |
Target Sequences: | NM_004910 NP_004901.2 O00562 |
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