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Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion.
Gene Name: | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
Family/Subfamily: | Non-Protein Kinase , not assigned-Non-Protein Kinase |
Synonyms: | PIP5K1B, MSS4, PIP5KIbeta, Protein STM-7, STM7, PIP5K1-beta, PtdIns(4)P-5-kinase 1 beta |
Target Sequences: | NM_003558 NP_003549.1 O14986 |
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