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PIP4K2B catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.
Gene Name: | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
Family/Subfamily: | Non-Protein Kinase , not assigned-Non-Protein Kinase |
Synonyms: | PIP4K2B, PI(5)P 4-kinase type II beta, PIP5K2B, PIP5KIIB, PTDINS(4)P-5-kinase, PI5P4KB, PIP5KIIbeta, PIP4KII-beta |
Target Sequences: | NM_003559 NP_003550.1 P78356 |
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