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Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.
Gene Name: | PIN2/TERF1 interacting, telomerase inhibitor 1 |
Synonyms: | PINX1, 67-11-3 protein, LPTS, PIN2 interacting protein 1, Pin2-interacting protein X1, LPTL, PIN2-interacting protein 1, Protein 67-11-3, TRF1-interacting protein 1 |
Target Sequences: | NM_017884 NP_060354.4 |
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