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PIK3R1 / p85 Alpha

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Gene Name: phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Family/Subfamily: Non-Protein Kinase , not assigned-Non-Protein Kinase
Synonyms: PIK3R1, p85, p85 Alpha, p85-ALPHA, PI3K regulatory subunit alpha, PI3-kinase subunit p85-alpha, GRB1
Target Sequences: M61906 P27986 P27986

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Products
Proteins (8)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (4)
PIK3R1 / p85 Alpha (8)
No (8)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His, N-Terminal (2)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (2)
Supernatant (1)
PIK3R1 / p85 Alpha Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PIK3R1 / p85 Alpha Protein - 12.5% SDS-PAGE of human PIK3R1 stained with Coomassie Blue
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Wheat Germ Extract
GST
75.68 kDa
10 µg/$479; 25 µg/$670
PIK3R1 / p85 Alpha Protein
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E. coli
6His, N-terminus
46 kDa
10 µg/$265; 100 µg/$365; 200 µg/$484; 50 µg/$315
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HEK 293 Cells
His, N-Terminal
~50 kDa
200 µl/$283
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HEK 293 Cells
His, N-Terminal
~50 kDa
100 µg/$298
PIK3R1 / p85 Alpha Protein - Purified recombinant protein PIK3R1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
53.3 kDa
20 µg/$1,107
PIK3R1 / p85 Alpha Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
53.3 kDa
20 µg/$150
PIK3R1 / p85 Alpha Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
53.3 kDa
100 µg/$494
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).